Effects of Pharmacologic Dopamine β-Hydroxylase Inhibition on Cocaine-Induced Reinstatement and Dopamine Neurochemistry in Squirrel Monkeys

Disulfiram has shown promise as a pharmacotherapy for cocaine dependence in clinical settings, although it has many targets, and the behavioral and molecular mechanisms underlying its efficacy are unclear. One of many biochemical actions of disulfiram is inhibition of dopamine β-hydroxylase (DBH), t...

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Bibliographic Details
Main Authors: Cooper, Debra A., Kimmel, Heather L., Manvich, Daniel F., Schmidt, Karl T., Weinshenker, David, Howell, Leonard L.
Format: Artigo
Language:Inglês
Published: The American Society for Pharmacology and Experimental Therapeutics 2014
Subjects:
Behavioral Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4056266/
https://ncbi.nlm.nih.gov/pubmed/24817036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.113.212357
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