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Cdc20 and securin overexpression predict short-term breast cancer survival

BACKGROUND: Cdc20 is an essential component of cell division and responsible for anaphase initiation regulated by securin degradation. Cdc20 function is strongly regulated by the spindle assembly checkpoint to ensure the timely separation of sister chromatids and integrity of the genome. We present...

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Autores principales: Karra, H, Repo, H, Ahonen, I, Löyttyniemi, E, Pitkänen, R, Lintunen, M, Kuopio, T, Söderström, M, Kronqvist, P
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4056061/
https://ncbi.nlm.nih.gov/pubmed/24853182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.252
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