Cdc20 and securin overexpression predict short-term breast cancer survival

BACKGROUND: Cdc20 is an essential component of cell division and responsible for anaphase initiation regulated by securin degradation. Cdc20 function is strongly regulated by the spindle assembly checkpoint to ensure the timely separation of sister chromatids and integrity of the genome. We present...

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Main Authors: Karra, H, Repo, H, Ahonen, I, Löyttyniemi, E, Pitkänen, R, Lintunen, M, Kuopio, T, Söderström, M, Kronqvist, P
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
Fag:
Molecular Diagnostics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4056061/
https://ncbi.nlm.nih.gov/pubmed/24853182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.252
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