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Immunosuppression through constitutively activated NF-κB signalling in human ovarian cancer and its reversal by an NF-κB inhibitor

BACKGROUND: Although T-cell immunity is thought to be involved in the prognosis of epithelial ovarian cancer (EOC) patients, immunosuppressive conditions hamper antitumour immune responses. Thus, their mechanisms and overcoming strategies need to be investigated. METHODS: The role of NF-κB in human...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Nishio, H, Yaguchi, T, Sugiyama, J, Sumimoto, H, Umezawa, K, Iwata, T, Susumu, N, Fujii, T, Kawamura, N, Kobayashi, A, Park, J, Aoki, D, Kawakami, Y
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4056060/
https://ncbi.nlm.nih.gov/pubmed/24867687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.251
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