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Carbon-11 labeled cathepsin K inhibitors: Syntheses and preliminary in vivo evaluation
Cathepsin K is a cysteine peptidase primarily located in osteoclasts, cells involved in normal growth and remodeling of bone but that are also responsible for bone loss in osteolytic diseases such as osteoporosis. In vivo imaging of cathepsin K may provide a method to assess changes in osteoclast nu...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4055946/ https://ncbi.nlm.nih.gov/pubmed/24637099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2014.02.004 |
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