Genetic Determinants of Long-Term Changes in Blood Lipid Concentrations: 10-Year Follow-Up of the GLACIER Study

Recent genome-wide meta-analyses identified 157 loci associated with cross-sectional lipid traits. Here we tested whether these loci associate (singly and in trait-specific genetic risk scores [GRS]) with longitudinal changes in total cholesterol (TC) and triglyceride (TG) levels in a population-bas...

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Hauptverfasser: Varga, Tibor V., Sonestedt, Emily, Shungin, Dmitry, Koivula, Robert W., Hallmans, Göran, Escher, Stefan A., Barroso, Inês, Nilsson, Peter, Melander, Olle, Orho-Melander, Marju, Renström, Frida, Franks, Paul W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055682/
https://ncbi.nlm.nih.gov/pubmed/24922540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004388
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