An Increase in Reactive Oxygen Species by Deregulation of ARNT Enhances Chemotherapeutic Drug-Induced Cancer Cell Death

BACKGROUND: Unique characteristics of tumor microenvironments can be used as targets of cancer therapy. The aryl hydrocarbon receptor nuclear translocator (ARNT) is an important mediator of tumor progression. However, the functional role of ARNT in chemotherapeutic drug-treated cancer remains unclea...

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Hlavní autoři: Shieh, Jiunn-Min, Shen, Chih-Jie, Chang, Wei-Chiao, Cheng, Hung-Chi, Chan, Ya-Yi, Huang, Wan-Chen, Chang, Wen-Chang, Chen, Ben-Kuen
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055634/
https://ncbi.nlm.nih.gov/pubmed/24921657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0099242
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