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β-catenin is overexpressed in hepatic fibrosis and blockage of Wnt/β-catenin signaling inhibits hepatic stellate cell activation

β-catenin, a core component of Wnt/β-catenin signaling, has been shown to be an important regulator of cellular proliferation and differentiation. Abnormal activation of Wnt/β-catenin signaling promotes tissue fibrogenesis. In the present study, the role of β-catenin during liver fibrogenesis was an...

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Hlavní autoři: GE, WEN-SONG, WANG, YAO-JUN, WU, JIAN-XIN, FAN, JIAN-GAO, CHEN, YING-WEI, ZHU, LIANG
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055486/
https://ncbi.nlm.nih.gov/pubmed/24691643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2014.2099
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