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Inhibition of high-mobility group box 1 expression by siRNA in rat hepatic stellate cells

AIM: To explore the role of high-mobility group box 1 (HMGB1) protein during liver fibrogenesis and investigate the functional effects of HMGB1 gene silencing in hepatic stellate cells (HSCs) using siRNA. METHODS: Hepatic fibrosis in rats was induced throu-gh serial subcutaneous injections of dimeth...

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Detalhes bibliográficos
Main Authors: Ge, Wen-Song, Wu, Jian-Xin, Fan, Jian-Gao, Wang, Yao-Jun, Chen, Ying-Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Co., Limited 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203359/
https://ncbi.nlm.nih.gov/pubmed/22039322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v17.i36.4090
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