Effects of topiramate on ethanol-cocaine interactions and DNA methyltransferase gene expression in the rat prefrontal cortex

BACKGROUND AND PURPOSE: Recent and ongoing clinical studies have indicated that topiramate (Topamax®) could be effective in treating ethanol or cocaine abuse. However, the effects of topiramate on the co-administration of ethanol and cocaine remain largely unknown. EXPERIMENTAL APPROACH: We studied...

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Bibliographic Details
Main Authors: Echeverry-Alzate, V, Giné, E, Bühler, K M, Calleja-Conde, J, Olmos, P, Gorriti, M A, Nadal, R, Rodríguez de Fonseca, F, López-Moreno, J A
Format: Artigo
Language:Inglês
Published: BlackWell Publishing Ltd 2014
Subjects:
Research Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055203/
https://ncbi.nlm.nih.gov/pubmed/24527678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12636
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