Developmental cues for the maturation of metabolic, electrophysiological and calcium handling properties of human pluripotent stem cell-derived cardiomyocytes

Human pluripotent stem cells (hPSCs), including embryonic and induced pluripotent stem cells, are abundant sources of cardiomyocytes (CMs) for cell replacement therapy and other applications such as disease modeling, drug discovery and cardiotoxicity screening. However, hPSC-derived CMs display imma...

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Autori principali: Keung, Wendy, Boheler, Kenneth R, Li, Ronald A
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
Soggetti:
Review
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055054/
https://ncbi.nlm.nih.gov/pubmed/24467782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/scrt406
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