Friedreich's ataxia induced pluripotent stem cell-derived cardiomyocytes display electrophysiological abnormalities and calcium handling deficiency

We sought to identify the impacts of Friedreich's ataxia (FRDA) on cardiomyocytes. FRDA is an autosomal recessive degenerative condition with neuronal and non-neuronal manifestations, the latter including progressive cardiomyopathy of the left ventricle, the leading cause of death in FRDA. Litt...

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Dades bibliogràfiques
Publicat a:Aging (Albany NY)
Autors principals: Crombie, Duncan E., Curl, Claire L., Raaijmakers, Antonia JA, Sivakumaran, Priyadharshini, Kulkarni, Tejal, Wong, Raymond CB, Minami, Itsunari, Evans-Galea, Marguerite V., Lim, Shiang Y., Delbridge, Lea, Corben, Louise A., Dottori, Mirella, Nakatsuji, Norio, Trounce, Ian A., Hewitt, Alex W., Delatycki, Martin B., Pera, Martin F., Pébay, Alice
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2017
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5472743/
https://ncbi.nlm.nih.gov/pubmed/28562313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101247
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