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Truncated and modified amyloid-beta species

Alzheimer’s disease pathology is closely connected to the processing of the amyloid precursor protein (APP) resulting in the formation of a variety of amyloid-beta (Aβ) peptides. They are found as insoluble aggregates in senile plaques, the histopathological hallmark of the disease. These peptides a...

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Bibliografiske detaljer
Main Authors: Kummer, Markus P, Heneka, Michael T
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055046/
https://ncbi.nlm.nih.gov/pubmed/25031638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/alzrt258
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