Efficient large-scale generation of functional hepatocytes from mouse embryonic stem cells grown in a rotating bioreactor with exogenous growth factors and hormones

INTRODUCTION: Embryonic stem (ES) cells are considered a potentially advantageous source of hepatocytes for both transplantation and the development of bioartificial livers. However, the efficient large-scale generation of functional hepatocytes from ES cells remains a major challenge, especially fo...

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Detalhes bibliográficos
Main Authors: Zhang, Shichang, Zhang, Yunping, Chen, Li, Liu, Tao, Li, Yangxin, Wang, Yingjie, Geng, Yongjian
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054944/
https://ncbi.nlm.nih.gov/pubmed/24294908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/scrt356
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