Cattle Mammary Bioreactor Generated by a Novel Procedure of Transgenic Cloning for Large-Scale Production of Functional Human Lactoferrin

Large-scale production of biopharmaceuticals by current bioreactor techniques is limited by low transgenic efficiency and low expression of foreign proteins. In general, a bacterial artificial chromosome (BAC) harboring most regulatory elements is capable of overcoming the limitations, but transferr...

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Detalhes bibliográficos
Main Authors: Yang, Penghua, Wang, Jianwu, Gong, Guochun, Sun, Xiuzhu, Zhang, Ran, Du, Zhuo, Liu, Ying, Li, Rong, Ding, Fangrong, Tang, Bo, Dai, Yunping, Li, Ning
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2565487/
https://ncbi.nlm.nih.gov/pubmed/18941633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003453
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