MOABS: model based analysis of bisulfite sequencing data

Bisulfite sequencing (BS-seq) is the gold standard for studying genome-wide DNA methylation. We developed MOABS to increase the speed, accuracy, statistical power and biological relevance of BS-seq data analysis. MOABS detects differential methylation with 10-fold coverage at single-CpG resolution b...

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Detalles Bibliográficos
Main Authors: Sun, Deqiang, Xi, Yuanxin, Rodriguez, Benjamin, Park, Hyun Jung, Tong, Pan, Meong, Mira, Goodell, Margaret A, Li, Wei
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2014
Assuntos:
Method
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054608/
https://ncbi.nlm.nih.gov/pubmed/24565500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2014-15-2-r38
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