hnRNP L and NF90 Interact with Hepatitis C Virus 5′-Terminal Untranslated RNA and Promote Efficient Replication

The 5′-terminal sequence of the hepatitis C virus (HCV) positive-strand RNA genome is essential for viral replication. Critical host factors, including a miR-122/Ago2 complex and poly(rC)-binding protein 2 (PCBP2), associate with this RNA segment. We used a biotinylated RNA pulldown approach to isol...

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Detalhes bibliográficos
Main Authors: Li, You, Masaki, Takahiro, Shimakami, Tetsuro, Lemon, Stanley M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054450/
https://ncbi.nlm.nih.gov/pubmed/24719423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00225-14
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