Kaposi's Sarcoma-Associated Herpesvirus-Encoded LANA Can Induce Chromosomal Instability through Targeted Degradation of the Mitotic Checkpoint Kinase Bub1

Kaposi's sarcoma-associated herpesvirus (KSHV) has a significant contributory role in the development of three major human neoplastic or lymphoproliferative diseases: Kaposi's sarcoma (KS), primary effusion lymphoma (PEL), and multicentric Castleman's disease (MCD). These diseases are...

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Bibliographic Details
Main Authors: Sun, Zhiguo, Xiao, Bingyi, Jha, Hem Chandra, Lu, Jie, Banerjee, Shuvomoy, Robertson, Erle S.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2014
Subjects:
Transformation and Oncogenesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054434/
https://ncbi.nlm.nih.gov/pubmed/24741095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00554-14
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