Bub1 and CENP-F Can Contribute to Kaposi's Sarcoma-Associated Herpesvirus Genome Persistence by Targeting LANA to Kinetochores

The latency-associated nuclear antigen (LANA) encoded by Kaposi's sarcoma-associated herpesvirus (KSHV) is critical for segregation of viral episomes to progeny nuclei and allows for maintenance of the viral genome in newly divided daughter cells. LANA binds to KSHV terminal repeat (TR) DNA and...

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Detalhes bibliográficos
Main Authors: Xiao, Bingyi, Verma, Subhash C., Cai, Qiliang, Kaul, Rajeev, Lu, Jie, Saha, Abhik, Robertson, Erle S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Cellular Response to Infection
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937805/
https://ncbi.nlm.nih.gov/pubmed/20660191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00713-10
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