Involvement of Hepatitis C Virus NS5A Hyperphosphorylation Mediated by Casein Kinase I-α in Infectious Virus Production

Nonstructural protein 5A (NS5A) of hepatitis C virus (HCV) possesses multiple functions in the viral life cycle. NS5A is a phosphoprotein that exists in hyperphosphorylated and basally phosphorylated forms. Although the phosphorylation status of NS5A is considered to have a significant impact on its...

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Detalhes bibliográficos
Main Authors: Masaki, Takahiro, Matsunaga, Satoko, Takahashi, Hirotaka, Nakashima, Kenji, Kimura, Yayoi, Ito, Masahiko, Matsuda, Mami, Murayama, Asako, Kato, Takanobu, Hirano, Hisashi, Endo, Yaeta, Lemon, Stanley M., Wakita, Takaji, Sawasaki, Tatsuya, Suzuki, Tetsuro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054430/
https://ncbi.nlm.nih.gov/pubmed/24760886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03170-13
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