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Prolonged Activity of the Pestiviral RNase E(rns) as an Interferon Antagonist after Uptake by Clathrin-Mediated Endocytosis

The RNase activity of the envelope glycoprotein E(rns) of the pestivirus bovine viral diarrhea virus (BVDV) is required to block type I interferon (IFN) synthesis induced by single-stranded RNA (ssRNA) and double-stranded RNA (dsRNA) in bovine cells. Due to the presence of an unusual membrane anchor...

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Detalhes bibliográficos
Main Authors: Zürcher, Christoph, Sauter, Kay-Sara, Mathys, Veronika, Wyss, Fabienne, Schweizer, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054414/
https://ncbi.nlm.nih.gov/pubmed/24741078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00672-14
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