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CTCF Binding to the First Intron of the Major Immediate Early (MIE) Gene of Human Cytomegalovirus (HCMV) Negatively Regulates MIE Gene Expression and HCMV Replication

Human cytomegalovirus (HCMV) gene expression during infection is highly regulated, with sequential expression of immediate-early (IE), early (E), and late (L) gene transcripts. To explore the potential role of chromatin regulatory factors that may regulate HCMV gene expression and DNA replication, w...

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Detalhes bibliográficos
Main Authors: Martínez, Francisco Puerta, Cruz, Ruth, Lu, Fang, Plasschaert, Robert, Deng, Zhong, Rivera-Molina, Yisel A., Bartolomei, Marisa S., Lieberman, Paul M., Tang, Qiyi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054410/
https://ncbi.nlm.nih.gov/pubmed/24741094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00845-14
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