Nuclear Magnetic Resonance Structure Revealed that the Human Polyomavirus JC Virus Agnoprotein Contains an α-Helix Encompassing the Leu/Ile/Phe-Rich Domain

Agnoprotein is a small multifunctional regulatory protein required for sustaining the productive replication of JC virus (JCV). It is a mostly cytoplasmic protein localizing in the perinuclear area and forms highly stable dimers/oligomers through a Leu/Ile/Phe-rich domain. There have been no three-d...

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Autors principals: Coric, Pascale, Saribas, A. Sami, Abou-Gharbia, Magid, Childers, Wayne, White, Martyn K., Bouaziz, Serge, Safak, Mahmut
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
Matèries:
Genome Replication and Regulation of Viral Gene Expression
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054343/
https://ncbi.nlm.nih.gov/pubmed/24672035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00146-14
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