Essential roles of Leu/Ile/Phe-rich domain of JC virus agnoprotein in dimer/oligomer formation, protein stability and splicing of viral transcripts

Agnoprotein is one of the key regulatory proteins of polyomaviruses, including JCV, BKV and SV40 and is required for a productive viral life cycle. We have recently reported that agnoprotein forms stable dimer/oligomers mediated by a predicted amphipathic α-helix, spanning amino acids (aa), 17 to 42...

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Hlavní autoři: Saribas, A. Sami, Abou-Gharbia, Magid, Childers, Wayne, Sariyer, Ilker K., White, Martyn K., Safak, Mahmut
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3777628/
https://ncbi.nlm.nih.gov/pubmed/23747198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2013.05.003
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