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The Pim-1 Protein Kinase Is an Important Regulator of MET Receptor Tyrosine Kinase Levels and Signaling

MET, the receptor for hepatocyte growth factor (HGF), plays an important role in signaling normal and tumor cell migration and invasion. Here, we describe a previously unrecognized mechanism that promotes MET expression in multiple tumor cell types. The levels of the Pim-1 protein kinase show a posi...

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מידע ביבליוגרפי
Main Authors: Cen, Bo, Xiong, Ying, Song, Jin H., Mahajan, Sandeep, DuPont, Rachel, McEachern, Kristen, DeAngelo, Daniel J., Cortes, Jorge E., Minden, Mark D., Ebens, Allen, Mims, Alice, LaRue, Amanda C., Kraft, Andrew S.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054323/
https://ncbi.nlm.nih.gov/pubmed/24777602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00147-14
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