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Endogenous Siderophore 2,5-Dihydroxybenzoic Acid Deficiency Promotes Anemia and Splenic Iron Overload in Mice

Eukaryotes produce a siderophore-like molecule via a remarkably conserved biosynthetic pathway. 3-OH butyrate dehydrogenase (BDH2), a member of the short-chain dehydrogenase (SDR) family of reductases, catalyzes a rate-limiting step in the biogenesis of the mammalian siderophore 2,5-dihydroxybenzoic...

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Bibliografiset tiedot
Päätekijät: Liu, Zhuoming, Ciocea, Alieta, Devireddy, L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054316/
https://ncbi.nlm.nih.gov/pubmed/24777603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00231-14
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