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From Hypothesis to Mechanism: Uncovering Nuclear Pore Complex Links to Gene Expression

The gene gating hypothesis put forth by Blobel in 1985 was an alluring proposal outlining functions for the nuclear pore complex (NPC) in transcription and nuclear architecture. Over the past several decades, collective studies have unveiled a full catalog of nucleoporins (Nups) that comprise the NP...

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Main Authors: Burns, Laura T., Wente, Susan R.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054283/
https://ncbi.nlm.nih.gov/pubmed/24615017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01730-13
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