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From Hypothesis to Mechanism: Uncovering Nuclear Pore Complex Links to Gene Expression

The gene gating hypothesis put forth by Blobel in 1985 was an alluring proposal outlining functions for the nuclear pore complex (NPC) in transcription and nuclear architecture. Over the past several decades, collective studies have unveiled a full catalog of nucleoporins (Nups) that comprise the NP...

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Autori principali: Burns, Laura T., Wente, Susan R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054283/
https://ncbi.nlm.nih.gov/pubmed/24615017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01730-13
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