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Integrated analysis of recurrent properties of cancer genes to identify novel drivers

The heterogeneity of cancer genomes in terms of acquired mutations complicates the identification of genes whose modification may exert a driver role in tumorigenesis. In this study, we present a novel method that integrates expression profiles, mutation effects, and systemic properties of mutated g...

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Detalhes bibliográficos
Main Authors: D'Antonio, Matteo, Ciccarelli, Francesca D
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054099/
https://ncbi.nlm.nih.gov/pubmed/23718799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2013-14-5-r52
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