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Integrated analysis of recurrent properties of cancer genes to identify novel drivers

The heterogeneity of cancer genomes in terms of acquired mutations complicates the identification of genes whose modification may exert a driver role in tumorigenesis. In this study, we present a novel method that integrates expression profiles, mutation effects, and systemic properties of mutated g...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: D'Antonio, Matteo, Ciccarelli, Francesca D
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054099/
https://ncbi.nlm.nih.gov/pubmed/23718799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2013-14-5-r52
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