PAR-CLIP data indicate that Nrd1-Nab3-dependent transcription termination regulates expression of hundreds of protein coding genes in yeast

BACKGROUND: Nrd1 and Nab3 are essential sequence-specific yeast RNA binding proteins that function as a heterodimer in the processing and degradation of diverse classes of RNAs. These proteins also regulate several mRNA coding genes; however, it remains unclear exactly what percentage of the mRNA co...

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Hauptverfasser: Webb, Shaun, Hector, Ralph D, Kudla, Grzegorz, Granneman, Sander
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053934/
https://ncbi.nlm.nih.gov/pubmed/24393166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2014-15-1-r8
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