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A Network of Interdependent Molecular Interactions Describes a Higher Order Nrd1-Nab3 Complex Involved in Yeast Transcription Termination

Nab3 and Nrd1 are yeast heterogeneous nuclear ribonucleoprotein (hnRNP)-like proteins that heterodimerize and bind RNA. Genetic and biochemical evidence reveals that they are integral to the termination of transcription of short non-coding RNAs by RNA polymerase II. Here we define a Nab3 mutation (n...

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Main Authors: Loya, Travis J., O'Rourke, Thomas W., Degtyareva, Natalya, Reines, Daniel
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2013
Teme:
RNA
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837157/
https://ncbi.nlm.nih.gov/pubmed/24100036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.516765
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