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The hnRNP-like Nab3 termination factor can employ heterologous prion-like domains in place of its own essential low complexity domain
Many RNA-binding proteins possess domains with a biased amino acid content. A common property of these low complexity domains (LCDs) is that they assemble into an ordered amyloid form, juxtaposing RNA recognition motifs in a subcellular compartment in which RNA metabolism is focused. Yeast Nab3 is o...
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| Publicado no: | PLoS One |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5638401/ https://ncbi.nlm.nih.gov/pubmed/29023495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0186187 |
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