Characterizing and measuring bias in sequence data

BACKGROUND: DNA sequencing technologies deviate from the ideal uniform distribution of reads. These biases impair scientific and medical applications. Accordingly, we have developed computational methods for discovering, describing and measuring bias. RESULTS: We applied these methods to the Illumin...

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Detalhes bibliográficos
Main Authors: Ross, Michael G, Russ, Carsten, Costello, Maura, Hollinger, Andrew, Lennon, Niall J, Hegarty, Ryan, Nusbaum, Chad, Jaffe, David B
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053816/
https://ncbi.nlm.nih.gov/pubmed/23718773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2013-14-5-r51
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