Global target mRNA specification and regulation by the RNA-binding protein ZFP36

BACKGROUND: ZFP36, also known as tristetraprolin or TTP, and ELAVL1, also known as HuR, are two disease-relevant RNA-binding proteins (RBPs) that both interact with AU-rich sequences but have antagonistic roles. While ELAVL1 binding has been profiled in several studies, the precise in vivo binding s...

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Autori principali: Mukherjee, Neelanjan, Jacobs, Nicholas C, Hafner, Markus, Kennington, Elizabeth A, Nusbaum, Jeffrey D, Tuschl, Thomas, Blackshear, Perry J, Ohler, Uwe
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053807/
https://ncbi.nlm.nih.gov/pubmed/24401661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2014-15-1-r12
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