Integrative regulatory mapping indicates that the RNA-binding protein HuR (ELAVL1) couples pre-mRNA processing and mRNA stability

RNA-binding proteins coordinate the fates of multiple RNAs, but the principles underlying these global interactions remain poorly understood. We elucidated regulatory mechanisms of the RNA-binding protein HuR, by integrating data from diverse high-throughput targeting technologies, specifically PAR-...

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Main Authors: Mukherjee, Neelanjan, Corcoran, David L., Nusbaum, Jeffrey D., Reid, David W., Georgiev, Stoyan, Hafner, Markus, Ascano, Manuel, Tuschl, Thomas, Ohler, Uwe, Keene, Jack D.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220597/
https://ncbi.nlm.nih.gov/pubmed/21723170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.06.007
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