BayMeth: improved DNA methylation quantification for affinity capture sequencing data using a flexible Bayesian approach

Affinity capture of DNA methylation combined with high-throughput sequencing strikes a good balance between the high cost of whole genome bisulfite sequencing and the low coverage of methylation arrays. We present BayMeth, an empirical Bayes approach that uses a fully methylated control sample to tr...

Full description

Saved in:
Bibliographic Details
Main Authors: Riebler, Andrea, Menigatti, Mirco, Song, Jenny Z, Statham, Aaron L, Stirzaker, Clare, Mahmud, Nadiya, Mein, Charles A, Clark, Susan J, Robinson, Mark D
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
Subjects:
Method
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053803/
https://ncbi.nlm.nih.gov/pubmed/24517713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2014-15-2-r35
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items