BayMeth: improved DNA methylation quantification for affinity capture sequencing data using a flexible Bayesian approach

Affinity capture of DNA methylation combined with high-throughput sequencing strikes a good balance between the high cost of whole genome bisulfite sequencing and the low coverage of methylation arrays. We present BayMeth, an empirical Bayes approach that uses a fully methylated control sample to tr...

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Detalhes bibliográficos
Main Authors: Riebler, Andrea, Menigatti, Mirco, Song, Jenny Z, Statham, Aaron L, Stirzaker, Clare, Mahmud, Nadiya, Mein, Charles A, Clark, Susan J, Robinson, Mark D
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Method
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053803/
https://ncbi.nlm.nih.gov/pubmed/24517713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2014-15-2-r35
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