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Advancing the functional utility of PAR-CLIP by quantifying background binding to mRNAs and lncRNAs
BACKGROUND: Sequence specific RNA binding proteins are important regulators of gene expression. Several related crosslinking-based, high-throughput sequencing methods, including PAR-CLIP, have recently been developed to determine direct binding sites of global protein-RNA interactions. However, no s...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4053780/ https://ncbi.nlm.nih.gov/pubmed/24393468 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2014-15-1-r2 |
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