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Characterizing 5-methylcytosine in the mammalian epitranscriptome

The post-transcriptional modification 5-methylcytosine (m(5)C) occurs in a wide range of coding and non-coding RNAs. We describe transcriptome-wide approaches to capture the global m(5)C RNA methylome. We also discuss the potential functions of m(5)C in RNA and compare them to 6-methyladenosine modi...

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Autors principals: Hussain, Shobbir, Aleksic, Jelena, Blanco, Sandra, Dietmann, Sabine, Frye, Michaela
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053770/
https://ncbi.nlm.nih.gov/pubmed/24286375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb4143
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