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All Your Base: a fast and accurate probabilistic approach to base calling
The accuracy of base calls produced by Illumina sequencers is adversely affected by several processes, with laser cross-talk and cluster phasing being prominent. We introduce an explicit statistical model of the sequencing process that generalizes current models of phasing and cross-talk and forms t...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
BioMed Central
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4053729/ https://ncbi.nlm.nih.gov/pubmed/22377270 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2012-13-2-r13 |
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