Genome-wide analysis of functional sirtuin chromatin targets in yeast

BACKGROUND: The sirtuins are a conserved family of NAD(+)-dependent histone/protein deacetylases that regulate numerous cellular processes, including heterochromatin formation and transcription. Multiple sirtuins are encoded by each eukaryotic genome, raising the possibility of cooperativity or func...

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Bibliographic Details
Main Authors: Li, Mingguang, Valsakumar, Veena, Poorey, Kunal, Bekiranov, Stefan, Smith, Jeffrey S
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053722/
https://ncbi.nlm.nih.gov/pubmed/23710766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2013-14-5-r48
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