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Promiscuity Is Not Always Bad
In the recent issue of Cell, Bonham et al. reveal that the sorting adapter TIRAP regulates the assembly of the myddosome upon Toll-like receptor activation from both the cell surface and endosomes through its promiscuous binding to lipids.
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4053647/ https://ncbi.nlm.nih.gov/pubmed/24766883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.04.009 |
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