ID4: a new player in the cancer arena

Id proteins (Id-1 to 4) are dominant negative regulators of basic helix-loop-helix transcription factors. They play a key role during development, preventing cell differentiation while inducing cell proliferation. They are poorly expressed in adult life but can be reactivated in tumorigenesis. Sever...

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Bibliographic Details
Main Authors: Dell'Orso, Stefania, Ganci, Federica, Strano, Sabrina, Blandino, Giovanni, Fontemaggi, Giulia
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2010
Subjects:
Research Perspective
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053547/
https://ncbi.nlm.nih.gov/pubmed/21293053
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