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Tailoring of Biomimetic High-Density Lipoprotein (HDL) Nanostructures Changes Cholesterol Binding and Efflux

Gold nanoparticles (Au NPs) were employed as templates to synthesize spherical, high-density lipoprotein (HDL) biomimics (HDL Au NPs) of different sizes and surface chemistries. The effect of size and surface chemistry on the cholesterol binding properties and the ability of the HDL Au NPs to efflux...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Luthi, Andrea J., Zhang, Heng, Kim, Dongwoo, Giljohann, David A., Mirkin, Chad A., Thaxton, C. Shad
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053472/
https://ncbi.nlm.nih.gov/pubmed/22117189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn2035457
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