Prenatal stress decreases Bdnf expression and increases methylation of Bdnf exon IV in rats

There is ample evidence that exposure to stress during gestation increases the risk of the offspring to develop mood disorders. Brain-derived neurotrophic factor (Bdnf) plays a critical role during neuronal development and is therefore a prime candidate to modulate neuronal signaling in adult offspr...

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Bibliografske podrobnosti
Main Authors: Boersma, Gretha J, Lee, Richard S, Cordner, Zachary A, Ewald, Erin R, Purcell, Ryan H, Moghadam, Alexander A, Tamashiro, Kellie L
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2014
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053462/
https://ncbi.nlm.nih.gov/pubmed/24365909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.27558
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