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Amino acid copolymers that alleviate experimental autoimmune encephalomyelitis (EAE) in vivo interact with heparan sulfates and gp96 in antigen presenting cells
Multiple Sclerosis (MS) is an autoimmune disease that affects the central nervous system. One approved treatment for relapsing forms of MS is YEAK, a random copolymer of the amino acids Tyr, Glu, Ala and Lys. YFAK, a second-generation copolymer composed of Tyr, Phe, Ala and Lys, is more successful i...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4053211/ https://ncbi.nlm.nih.gov/pubmed/23740953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300345 |
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