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ERβ1 represses basal-like breast cancer epithelial to mesenchymal transition by destabilizing EGFR

INTRODUCTION: Epithelial to mesenchymal transition (EMT) is associated with the basal-like breast cancer phenotypes. Sixty percent of basal-like cancers have been shown to express wild-type estrogen receptor beta (ERβ1). However, it is still unclear whether the ERβ expression is related to EMT, inva...

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Hlavní autoři: Thomas, Christoforos, Rajapaksa, Gayani, Nikolos, Fotis, Hao, Ruixin, Katchy, Anne, McCollum, Catherine W, Bondesson, Maria, Quinlan, Phil, Thompson, Alastair, Krishnamurthy, Savitri, Esteva, Francisco J, Gustafsson, Jan-Åke
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053135/
https://ncbi.nlm.nih.gov/pubmed/23158001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3358
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