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Chemosensitivity and p53; new tricks by an old dog
The effect of TP53 mutations on chemosensitivity in breast cancer is a controversial issue. In an elegant paper in Cancer Cell, Jackson and colleagues report wtp53 protein to block anti-tumour effects of doxorubicin treatment in mice. p53 did so by inducing senescence, thereby preventing mitotic cat...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4053121/ https://ncbi.nlm.nih.gov/pubmed/23131146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3326 |
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