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The Impact of Aging on Cancer Vaccination
Cancer vaccination is less effective at old than at young age, due to T cell unresponsiveness, caused by various age-related changes of the immune system. This includes lack of naïve T cells, defects in activation pathways of T cells and antigen-presenting cells (APC), and age-related changes in the...
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| Formato: | Artigo |
| Idioma: | Inglês |
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2011
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4052947/ https://ncbi.nlm.nih.gov/pubmed/21763118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2011.05.003 |
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